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Admin06.07.2021

Structure of the Glycosyltransferase Ktr4p from Saccharomyces cerevisiae

This modified program was used to identify potential homologs of Dak PDB IDs 1oi2 and 1un8.
2807
Admin27.07.2021

Crystal structures of a novel anti

4, including reading and contouring of electron-density maps.
303
Admin25.08.2021

Structural basis for dolichylphosphate mannose biosynthesis

Fold [48178] 1 superfamily multihelical; common core is formed around two long antiparallel helices related by pseudo twofold symmetry• S1 Fig: Model of Donor- and Acceptor Sugar Binding.
Admin14.06.2021

LOC110889491 GDP

Figures were prepared in PyMOL [].
9909
Admin03.07.2021

CDD Conserved Protein Domain Family: LbH_M1P_guanylylT_C

Cells with low levels of PMI are sensitive to mannose, whereas cells with high levels are resistant, but can be made sensitive by RNA-interference-mediated depletion of the enzyme.
3901
Admin12.07.2021

Waterfall D

Mechanistically, mannose is taken up by the same transporter s as glucose 3 but accumulates as mannose-6-phosphate in cells, and this impairs the further metabolism of glucose in glycolysis, the tricarboxylic acid cycle, the pentose phosphate pathway and glycan synthesis.
4601
Admin11.07.2021

EDD, a novel phosphotransferase domain common to mannose transporter EIIA, dihydroxyacetone kinase, and DegV

In the meantime, taking D-Mannose with food and has been reported to help.
Admin02.07.2021

CDD Conserved Protein Domain Family: M1P_guanylylT_A_like_N

However, the construct used for crystallisation encompasses the membrane-proximal stalk domain in addition to the catalytic domain.
5508
Admin23.06.2021

CDD Conserved Protein Domain Family: LbH_M1P_guanylylT_C

Of the eight studies reporting on D-mannose in this context, six were clinical and included 695 individuals.
4010
Admin06.07.2021

Waterfall D

GDP-mannose pyrophosphorylase GTP: alpha-d-mannose-1-phosphate guanyltransferase catalyzes the formation of GDP-d-mannose from GTP and alpha-d-mannose-1-Phosphate.
5402
Admin28.07.2021

EDD, a novel phosphotransferase domain common to mannose transporter EIIA, dihydroxyacetone kinase, and DegV

The arrows stem from data points corresponding to query sequences that when used in PSI-BLAST establish evolutionary links across families to the data points representing sequence hits.
2905